TY - JOUR
T1 - Potent bactericidal activity of silver nanoparticles synthesized from Cassia fistula fruit
AU - Rashid, Muhammad Imtiaz
AU - Mujawar, Liyakat Hamid
AU - Mujallid, Mohammad Ibrahim
AU - Shahid, Muhammad
AU - Rehan, Zulfiqar Ahmad
AU - Khan, Muhammad Kashif Iqbal
AU - Ismail, Iqbal M.I.
N1 - Publisher Copyright:
© 2017 Elsevier Ltd
PY - 2017/6/1
Y1 - 2017/6/1
N2 - We demonstrated one-step synthesis of silver nanoparticles (AgNPs) from Cassia fistula fruit extract and their antibacterial activity against E. coli and K. pneumoniae. Biogenic AgNPs were characterized by scanning electron microscopy, X-Ray diffraction and fourier transform infrared spectroscopy. Results confirmed spherical shaped AgNPs with an average crystallite size of ∼69 nm. Dose-dependent (0, 10, 20, 40 and 80 μg mL−1) growth kinetic studies showed 100% potency against E. coli (20 μg mL−1) and K. pneumoniae (80 μg mL−1) after 1 and 5 h, respectively. Surface morphology analysis revealed formation of groove/pits in the lysed cell membrane that eventually led to bacterial death.
AB - We demonstrated one-step synthesis of silver nanoparticles (AgNPs) from Cassia fistula fruit extract and their antibacterial activity against E. coli and K. pneumoniae. Biogenic AgNPs were characterized by scanning electron microscopy, X-Ray diffraction and fourier transform infrared spectroscopy. Results confirmed spherical shaped AgNPs with an average crystallite size of ∼69 nm. Dose-dependent (0, 10, 20, 40 and 80 μg mL−1) growth kinetic studies showed 100% potency against E. coli (20 μg mL−1) and K. pneumoniae (80 μg mL−1) after 1 and 5 h, respectively. Surface morphology analysis revealed formation of groove/pits in the lysed cell membrane that eventually led to bacterial death.
KW - Biogenic
KW - Gram negative bacteria
KW - MIC
KW - Silver nanoparticles
KW - X-ray techniques
UR - http://www.scopus.com/inward/record.url?scp=85018510934&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018510934&partnerID=8YFLogxK
U2 - 10.1016/j.micpath.2017.03.048
DO - 10.1016/j.micpath.2017.03.048
M3 - Article
C2 - 28416381
AN - SCOPUS:85018510934
SN - 0882-4010
VL - 107
SP - 354
EP - 360
JO - Microbial Pathogenesis
JF - Microbial Pathogenesis
ER -