Highly Sensitive and Selective Voltammetric Sensor Fullerene Modified Glassy Carbon Electrode for Determination of Cefitizoxime in Solubilized System

Rajeev Jain; Jahangir Ahmad Rather; Ashish Dwivedi; Vikas

doi:10.1002/elan.201000243

Highly Sensitive and Selective Voltammetric Sensor Fullerene Modified Glassy Carbon Electrode for Determination of Cefitizoxime in Solubilized System

Rajeev Jain^*, Jahangir Ahmad Rather, Ashish Dwivedi, Vikas

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

The usefulness of fullerene modified glassy carbon electrode in mediating the reduction of cefitizoxime in solubilized system has been demonstrated. Due to the unique structure and extraordinary properties, fullerene shows higher catalytic efficiency towards cefitizoxime reduction. The kinetic parameters, electron transfer coefficient (α) and rate constant (K₀) across the modified electrode are 0.37 and 0.1081/s respectively. The proposed square-wave voltammetric method is linear over the concentration range 1.2-10.3 μg/mL. The limit of detection (LOD) is found 0.27 ng/mL. High sensitivity and selectivity together with low detection limit of the electrode response make it suitable for the determination of cefitizoxime.

Original language	English
Pages (from-to)	2600-2606
Number of pages	7
Journal	Electroanalysis
Volume	22
Issue number	21
DOIs	https://doi.org/10.1002/elan.201000243
Publication status	Published - Nov 2010
Externally published	Yes

Keywords

Cefitizoxime (Ceftz.)
Cetyltrimethylammonium bromide (CTAB)
Fullerene modified glassy carbon electrode (C-GCE)
Sensors

ASJC Scopus subject areas

Analytical Chemistry
Electrochemistry

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10.1002/elan.201000243

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title = "Highly Sensitive and Selective Voltammetric Sensor Fullerene Modified Glassy Carbon Electrode for Determination of Cefitizoxime in Solubilized System",

abstract = "The usefulness of fullerene modified glassy carbon electrode in mediating the reduction of cefitizoxime in solubilized system has been demonstrated. Due to the unique structure and extraordinary properties, fullerene shows higher catalytic efficiency towards cefitizoxime reduction. The kinetic parameters, electron transfer coefficient (α) and rate constant (K0) across the modified electrode are 0.37 and 0.1081/s respectively. The proposed square-wave voltammetric method is linear over the concentration range 1.2-10.3 μg/mL. The limit of detection (LOD) is found 0.27 ng/mL. High sensitivity and selectivity together with low detection limit of the electrode response make it suitable for the determination of cefitizoxime.",

keywords = "Cefitizoxime (Ceftz.), Cetyltrimethylammonium bromide (CTAB), Fullerene modified glassy carbon electrode (C-GCE), Sensors",

author = "Rajeev Jain and Rather, {Jahangir Ahmad} and Ashish Dwivedi and Vikas",

year = "2010",

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doi = "10.1002/elan.201000243",

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volume = "22",

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journal = "Electroanalysis",

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T1 - Highly Sensitive and Selective Voltammetric Sensor Fullerene Modified Glassy Carbon Electrode for Determination of Cefitizoxime in Solubilized System

AU - Jain, Rajeev

AU - Rather, Jahangir Ahmad

AU - Dwivedi, Ashish

AU - Vikas,

PY - 2010/11

Y1 - 2010/11

N2 - The usefulness of fullerene modified glassy carbon electrode in mediating the reduction of cefitizoxime in solubilized system has been demonstrated. Due to the unique structure and extraordinary properties, fullerene shows higher catalytic efficiency towards cefitizoxime reduction. The kinetic parameters, electron transfer coefficient (α) and rate constant (K0) across the modified electrode are 0.37 and 0.1081/s respectively. The proposed square-wave voltammetric method is linear over the concentration range 1.2-10.3 μg/mL. The limit of detection (LOD) is found 0.27 ng/mL. High sensitivity and selectivity together with low detection limit of the electrode response make it suitable for the determination of cefitizoxime.

AB - The usefulness of fullerene modified glassy carbon electrode in mediating the reduction of cefitizoxime in solubilized system has been demonstrated. Due to the unique structure and extraordinary properties, fullerene shows higher catalytic efficiency towards cefitizoxime reduction. The kinetic parameters, electron transfer coefficient (α) and rate constant (K0) across the modified electrode are 0.37 and 0.1081/s respectively. The proposed square-wave voltammetric method is linear over the concentration range 1.2-10.3 μg/mL. The limit of detection (LOD) is found 0.27 ng/mL. High sensitivity and selectivity together with low detection limit of the electrode response make it suitable for the determination of cefitizoxime.

KW - Cefitizoxime (Ceftz.)

KW - Cetyltrimethylammonium bromide (CTAB)

KW - Fullerene modified glassy carbon electrode (C-GCE)

KW - Sensors

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Highly Sensitive and Selective Voltammetric Sensor Fullerene Modified Glassy Carbon Electrode for Determination of Cefitizoxime in Solubilized System

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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