TY - JOUR
T1 - Highly Sensitive and Selective Voltammetric Sensor Fullerene Modified Glassy Carbon Electrode for Determination of Cefitizoxime in Solubilized System
AU - Jain, Rajeev
AU - Rather, Jahangir Ahmad
AU - Dwivedi, Ashish
AU - Vikas,
PY - 2010/11
Y1 - 2010/11
N2 - The usefulness of fullerene modified glassy carbon electrode in mediating the reduction of cefitizoxime in solubilized system has been demonstrated. Due to the unique structure and extraordinary properties, fullerene shows higher catalytic efficiency towards cefitizoxime reduction. The kinetic parameters, electron transfer coefficient (α) and rate constant (K0) across the modified electrode are 0.37 and 0.1081/s respectively. The proposed square-wave voltammetric method is linear over the concentration range 1.2-10.3 μg/mL. The limit of detection (LOD) is found 0.27 ng/mL. High sensitivity and selectivity together with low detection limit of the electrode response make it suitable for the determination of cefitizoxime.
AB - The usefulness of fullerene modified glassy carbon electrode in mediating the reduction of cefitizoxime in solubilized system has been demonstrated. Due to the unique structure and extraordinary properties, fullerene shows higher catalytic efficiency towards cefitizoxime reduction. The kinetic parameters, electron transfer coefficient (α) and rate constant (K0) across the modified electrode are 0.37 and 0.1081/s respectively. The proposed square-wave voltammetric method is linear over the concentration range 1.2-10.3 μg/mL. The limit of detection (LOD) is found 0.27 ng/mL. High sensitivity and selectivity together with low detection limit of the electrode response make it suitable for the determination of cefitizoxime.
KW - Cefitizoxime (Ceftz.)
KW - Cetyltrimethylammonium bromide (CTAB)
KW - Fullerene modified glassy carbon electrode (C-GCE)
KW - Sensors
UR - http://www.scopus.com/inward/record.url?scp=77958523398&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77958523398&partnerID=8YFLogxK
U2 - 10.1002/elan.201000243
DO - 10.1002/elan.201000243
M3 - Article
AN - SCOPUS:77958523398
SN - 1040-0397
VL - 22
SP - 2600
EP - 2606
JO - Electroanalysis
JF - Electroanalysis
IS - 21
ER -