Bilateral Gonadoblastoma Overgrown by Dysgerminoma of the Right Gonad in a Patient with Swyer Syndrome

Mohammad Arafa; Marwa Al Ryiami; Maryam Al Shukri; Ikram Burney; Yasser Mahfouz; Nashwa Al-Kindi

doi:10.26574/maedica.2020.16.4.734

Bilateral Gonadoblastoma Overgrown by Dysgerminoma of the Right Gonad in a Patient with Swyer Syndrome

Mohammad Arafa, Marwa Al Ryiami, Maryam Al Shukri, Ikram Burney, Yasser Mahfouz, Nashwa Al-Kindi

Research output: Contribution to journal › Article › peer-review

Abstract

Patients with Swyer syndrome, "XY gonadal dysgenesis", have fibrosed gonads with a significant risk of developing germ cell tumours. During radiological assessment, a 17-year-old female with Swyer syndrome showed mildly enlarged gonads that were removed laparoscopically and proved pathologically to be bilateral gonadoblastomas. In addition, the right sided lesion showed overgrowth by dysgerminoma. The patient was further treated with combination chemotherapy and she was in complete remission for three years.

Original language	English
Pages (from-to)	734-737
Number of pages	4
Journal	Maedica
Volume	16
Issue number	4
DOIs	https://doi.org/10.26574/maedica.2020.16.4.734
Publication status	Published - Dec 2021

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10.26574/maedica.2020.16.4.734

Cite this

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title = "Bilateral Gonadoblastoma Overgrown by Dysgerminoma of the Right Gonad in a Patient with Swyer Syndrome",

abstract = "Patients with Swyer syndrome, {"}XY gonadal dysgenesis{"}, have fibrosed gonads with a significant risk of developing germ cell tumours. During radiological assessment, a 17-year-old female with Swyer syndrome showed mildly enlarged gonads that were removed laparoscopically and proved pathologically to be bilateral gonadoblastomas. In addition, the right sided lesion showed overgrowth by dysgerminoma. The patient was further treated with combination chemotherapy and she was in complete remission for three years.",

author = "Mohammad Arafa and Ryiami, {Marwa Al} and Shukri, {Maryam Al} and Ikram Burney and Yasser Mahfouz and Nashwa Al-Kindi",

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AU - Arafa, Mohammad

AU - Ryiami, Marwa Al

AU - Shukri, Maryam Al

AU - Burney, Ikram

AU - Mahfouz, Yasser

AU - Al-Kindi, Nashwa

PY - 2021/12

Y1 - 2021/12

N2 - Patients with Swyer syndrome, "XY gonadal dysgenesis", have fibrosed gonads with a significant risk of developing germ cell tumours. During radiological assessment, a 17-year-old female with Swyer syndrome showed mildly enlarged gonads that were removed laparoscopically and proved pathologically to be bilateral gonadoblastomas. In addition, the right sided lesion showed overgrowth by dysgerminoma. The patient was further treated with combination chemotherapy and she was in complete remission for three years.

AB - Patients with Swyer syndrome, "XY gonadal dysgenesis", have fibrosed gonads with a significant risk of developing germ cell tumours. During radiological assessment, a 17-year-old female with Swyer syndrome showed mildly enlarged gonads that were removed laparoscopically and proved pathologically to be bilateral gonadoblastomas. In addition, the right sided lesion showed overgrowth by dysgerminoma. The patient was further treated with combination chemotherapy and she was in complete remission for three years.

U2 - 10.26574/maedica.2020.16.4.734

DO - 10.26574/maedica.2020.16.4.734

M3 - Article

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