Abstract
Several types of vaccines have been approved to prevent SARS-CoV-2 infection. Few studies are conducted on the efficacy of COVID-19 vaccines. Vaccination is important to eliminate and fight SARS-CoV-2 infection and several vaccines have been approved. This study aimed to assess the incidence density of COVID-19 infection among the community, estimate the effectiveness of different types of vaccines (inactivated virus, viral vector or mRNA) and efficiency of incomplete and complete vaccination. In this observational cross-sectional study, a total of 4924 specimens were received from 1st January 2022 to 2nd February 2022 for the detection of SARS-CoV-2. The patient’s age, gender, and vaccination data were recorded and S, N, and ORF 1ab genes were amplified after RNA extraction through PCR. out of which 1034 (20.99 %) cases were positive. Among 1034 (20.99 %) positive cases, 418 and 616 patients were vaccinated and non-vaccinated respectively. The cases of SARS-CoV-2 in vaccinated patients were categorized into a sudden infection (≤ 10 days) and late infection (≥10 days) after the incomplete and complete dose of vaccination. Vaccination provides partial protection against SARS-CoV-2 infection. This might be due to the low efficacy and inability to detect recent variations in the protein structure of the virus.
Original language | English |
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Pages (from-to) | 377-382 |
Number of pages | 6 |
Journal | Proceedings of the Pakistan Academy of Sciences: Part B |
Volume | 60 |
Issue number | 3 |
DOIs | |
Publication status | Published - Aug 24 2023 |
Keywords
- COVID-19 Vaccine Types
- Ct Valu
- SARS-COV-2
- Vaccine Effectiveness
ASJC Scopus subject areas
- General Biochemistry,Genetics and Molecular Biology
- General Environmental Science
- General Agricultural and Biological Sciences