Treatment of malabsorption vitamin D deficiency myopathy with intramuscular vitamin D

Saif Alyaarubi, Celia Rodd

نتاج البحث: المساهمة في مجلةArticleمراجعة النظراء

8 اقتباسات (Scopus)


A nearly 5 year-old boy presented with proximal muscle weakness, reduced muscle bulk, a positive Gower sign and Trendelenburg gait. He was known to have cholestatic liver disease. Investigations revealed markedly low serum total calcium, elevated alkaline phosphatase, very low serum 25-hydroxyvitamin D, and radiographs consistent with active rickets despite the ongoing administration of a water-soluble preparation of vitamin D. Only i.v. calcitriol acutely corrected the hypocalcemia, despite trying several oral preparations, suggesting that malabsorption secondary to chronic liver disease was the cause of his rickets. Intramuscular calciferol quickly corrected his muscle weakness and X-ray findings. Myopathy secondary to vitamin D deficiency is an uncommon diagnosis in children. Intermittent calciferol is an inexpensive and practical treatment for vitamin D deficiency, especially if associated with malabsorption.

اللغة الأصليةEnglish
الصفحات (من إلى)719-722
عدد الصفحات4
دوريةJournal of Pediatric Endocrinology and Metabolism
مستوى الصوت18
رقم الإصدار7
المعرِّفات الرقمية للأشياء
حالة النشرPublished - يوليو 2005
منشور خارجيًانعم

ASJC Scopus subject areas

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