TY - JOUR
T1 - 262 Comparative investigation of haplotypes in a cohort of unrelated healthy volunteers and Omani CF patients
AU - Ruhaili, M.S. Al
AU - Moqbali, T.A. Al
AU - Kindi, A.K. Al
AU - Salmani, M. Al
AU - Shivalingam, G.
AU - Fass, U.W.
PY - 2016/6
Y1 - 2016/6
N2 - Correlations were found between FEV 1 , BMI and CFRD. A steeper decline of FEV 1 was found in patients with PI and fungi colonization. The 6MWT was performed by 62% of the patients. Correlations were found between desaturation and lower FEV 1 , higher Residual Volume and increased number of PEX. Correlations were also identified between walked distance and fungi colonization, PaO2 at rest and PEx. Conclusion: PI and fungi colonization were the major markers of disease severity, characterized by a steeper decline in FEV 1. Desaturation in the 6MWT is linked to a higher number of PEx and fungi colonization also seems to be correlated with a more significant compromise in exercise capacity.
AB - Correlations were found between FEV 1 , BMI and CFRD. A steeper decline of FEV 1 was found in patients with PI and fungi colonization. The 6MWT was performed by 62% of the patients. Correlations were found between desaturation and lower FEV 1 , higher Residual Volume and increased number of PEX. Correlations were also identified between walked distance and fungi colonization, PaO2 at rest and PEx. Conclusion: PI and fungi colonization were the major markers of disease severity, characterized by a steeper decline in FEV 1. Desaturation in the 6MWT is linked to a higher number of PEx and fungi colonization also seems to be correlated with a more significant compromise in exercise capacity.
UR - https://www.mendeley.com/catalogue/705837eb-93fe-3a06-b51d-abbe56d597cf/
U2 - 10.1016/s1569-1993(16)30500-8
DO - 10.1016/s1569-1993(16)30500-8
M3 - Article
SN - 1569-1993
VL - 15
SP - S118
JO - Journal of Cystic Fibrosis
JF - Journal of Cystic Fibrosis
ER -