Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult

Ramachandiran Nandhagopal; Nelly Khmeleva; B. Jayakrishnan; Teresa White; Faisal Al Azri; Jojy George; Anna Heintzman; Khalfan A. Al Zeedy; Lucy Rorke-Adams; Arunodaya R. Gujjar; D. Scott Schmid; Abdullah Al-Asmi; Maria A. Nagel; Poovathoor Chacko Jacob; Don Gilden

doi:10.1093/ofid/ofu064

Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult

Ramachandiran Nandhagopal, Nelly Khmeleva, B. Jayakrishnan, Teresa White, Faisal Al Azri, Jojy George, Anna Heintzman, Khalfan A. Al Zeedy, Lucy Rorke-Adams, Arunodaya R. Gujjar, D. Scott Schmid, Abdullah Al-Asmi, Maria A. Nagel, Poovathoor Chacko Jacob, Don Gilden^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.

Original language	English
Journal	Open Forum Infectious Diseases
Volume	1
Issue number	2
DOIs	https://doi.org/10.1093/ofid/ofu064
Publication status	Published - Sept 1 2014

Keywords

Absence of rash
Brainstem encephalitis
Pneumonitis
VZV

ASJC Scopus subject areas

Infectious Diseases
Oncology

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Nandhagopal, R., Khmeleva, N., Jayakrishnan, B., White, T., Al Azri, F., George, J., Heintzman, A., Al Zeedy, K. A., Rorke-Adams, L., Gujjar, A. R., Schmid, D. S., Al-Asmi, A., Nagel, M. A., Jacob, P. C., & Gilden, D. (2014). Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult. Open Forum Infectious Diseases, 1(2). https://doi.org/10.1093/ofid/ofu064

Nandhagopal, R, Khmeleva, N, Jayakrishnan, B, White, T, Al Azri, F , George, J, Heintzman, A, Al Zeedy, KA, Rorke-Adams, L, Gujjar, AR, Schmid, DS, Al-Asmi, A, Nagel, MA, Jacob, PC & Gilden, D 2014, 'Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult', Open Forum Infectious Diseases, vol. 1, no. 2. https://doi.org/10.1093/ofid/ofu064

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abstract = "Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.",

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AU - White, Teresa

AU - Al Azri, Faisal

AU - George, Jojy

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Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult

Abstract

Keywords

ASJC Scopus subject areas

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