TY - JOUR
T1 - Unlocking the Anticancer Potential of Frankincense Essential Oils (FEOs) Through Nanotechnology
T2 - A Review
AU - Al-Balushi, Rayya A.
AU - Haque, Ashanul
AU - Saeed, Mohd
AU - Al-Harthy, Thuraya
AU - Al-Hinaai, Mohammed
AU - Al-Hashmi, Salim
N1 - © 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2023/11/1
Y1 - 2023/11/1
N2 - Cancer is a group of heterogeneous diseases that occur when cells in the body proliferate and divide uncontrollably. As the current treatment modalities have pros and cons, the discovery of new chemotherapeutic agents with the least side effects is one of the most investigated research areas. In this context, plant-based natural products are a rich source of drugs and have served humanity for ages. Frankincense essential oils (FEOs) are among the most promising plant-based oils in Gulf countries. In addition to their high cultural value, FEOs are also famous for their engaging biological activities, including anti-cancerous. However, the practical application of FEOs is often hindered/by their low water solubility, limited bioavailability, high volatility, and sensitivity toward heat, humidity, light, or oxygen. Thus, a significant demand for technological advancement would improve their ability to target particular cells and tissues. Nanotechnology emerged as an exciting approach in this context. Through suitable nano-formulation (functionalization or encapsulation into a nanostructure), issues arising due to solubility, targeting capability, and delivery can be controlled.
AB - Cancer is a group of heterogeneous diseases that occur when cells in the body proliferate and divide uncontrollably. As the current treatment modalities have pros and cons, the discovery of new chemotherapeutic agents with the least side effects is one of the most investigated research areas. In this context, plant-based natural products are a rich source of drugs and have served humanity for ages. Frankincense essential oils (FEOs) are among the most promising plant-based oils in Gulf countries. In addition to their high cultural value, FEOs are also famous for their engaging biological activities, including anti-cancerous. However, the practical application of FEOs is often hindered/by their low water solubility, limited bioavailability, high volatility, and sensitivity toward heat, humidity, light, or oxygen. Thus, a significant demand for technological advancement would improve their ability to target particular cells and tissues. Nanotechnology emerged as an exciting approach in this context. Through suitable nano-formulation (functionalization or encapsulation into a nanostructure), issues arising due to solubility, targeting capability, and delivery can be controlled.
KW - Anticancer
KW - Breast cancer
KW - Essential oil
KW - Frankincense
KW - Melanoma
KW - Nanoformulations
UR - http://www.scopus.com/inward/record.url?scp=85175379472&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85175379472&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/1d685acc-f5b8-3ef3-b556-8f2d86c3ff0f/
U2 - 10.1007/s12033-023-00918-5
DO - 10.1007/s12033-023-00918-5
M3 - Article
C2 - 37914864
AN - SCOPUS:85175379472
SN - 1073-6085
JO - Molecular Biotechnology
JF - Molecular Biotechnology
ER -