Transient myeloproliferative disorder and Down syndrome: Is there a link?

Zenaida S. Reyes, Wafa Bashir, Anil Pathare

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


An extremely premature male neonate presented with an unusual multisystem dysfunction within the first 24 to 48 hours of life. The unfolding of clinical events and investigations revealed a transient myeloproliferative disorder (TMD). TMD was the main indication for karyotyping of this premature infant without clinical symptoms of Down syndrome. The awareness of TMD in a newborn warrants karyotype analysis to look for trisomy 21 and a close surveillance because of its potential progression to true leukaemia.

Original languageEnglish
Pages (from-to)498-502
Number of pages5
JournalSultan Qaboos University Medical Journal
Issue number4
Publication statusPublished - Nov 2012


  • Acute myelogenous leukemia (AML)
  • Case report
  • Down syndrome
  • Extreme premature
  • GATA1
  • Oman
  • Transient myeloproliferative disorder

ASJC Scopus subject areas

  • Medicine(all)


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