Spectrum of cerebral venous thrombosis in Oman

Darshan Lal, Arunodaya R. Gujjar*, Nandagopal Ramachandiran, Ammar Obaidi, Sunil Kumar, Mortada El-Tigani, Faizal Al-Azri, Abdullah R. Al-Asmi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Objectives: Cerebral venous thrombosis (CVT) can have varied and life-threatening manifestations. This study aimed to examine the spectrum of its clinical presentations and outcomes in a tertiary hospital in Oman. Methods: This retrospective study was conducted at the Sultan Qaboos University Hospital, Muscat, Oman, between January 2009 and December 2017. The medical records of all patients with CVT were reviewed to determine demographic characteristics, clinical features and patient outcomes. Results: A total of 30 patients had CVT. The mean age was 36.8 ± 11 years and the male-to-female ratio was 2:3. Common manifestations included headache (83%), altered sensorium (50%), seizures (43%) and hemiparesis (33%). Underlying risk factors were present in 16 patients (53%). Computed tomography or magnetic resonance imaging of the brain was abnormal in all patients, with indications of infarcts (40%) and major sinus thrombosis (100%). There were five cases (20%) of deep CVT. The patients were treated with low-molecular-weight heparin, mannitol and anticonvulsants. The majority (77%) had no residual neurological deficits at follow-up. Conclusion: These findings indicate that CVT is a relatively uncommon yet treatable disorder in Oman. A high index of suspicion, early diagnosis, prompt anticoagulation treatment and critical care may enhance favourable patient outcomes.

Original languageEnglish
Pages (from-to)e329-e337
JournalSultan Qaboos University Medical Journal
Volume18
Issue number3
DOIs
Publication statusPublished - Aug 2018

Keywords

  • Cerebral thrombosis
  • Cranial venous sinuses
  • Neurological manifestations
  • Oman
  • Patient Outcome assessment
  • Venous thrombosis

ASJC Scopus subject areas

  • General Medicine

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