Pyridoxine-dependent seizures: 10-year follow-up of eight cases

Roshan Koul*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Eight children with pyridoxine-dependent seizures (PDS) were seen over a period of 10 years. Of those children, 6 are on regular follow-up. Four of the children were seen in one family. All the patients presented with refractory seizures, mainly neonatal status epilepticus. Though PDS is a rare condition, it must be considered in all cases with refractory seizures, particularly in childrens younger than 3 years. When confirming a diagnosis, oral pyridoxine is as effective as intravenous pyridoxine.

Original languageEnglish
Pages (from-to)460-463
Number of pages4
JournalNeurology India
Issue number4
Publication statusPublished - Oct 1 2009


  • Neonatal status epilepticus
  • Pyridoxine
  • Pyridoxine dependency
  • Refractory seizures

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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