TY - JOUR
T1 - Proteomics: Concepts and applications in human medicine
T2 - Concepts and applications in human medicine
AU - Al-Amrani, Safa
AU - Al-Jabri, Zaaima
AU - Al-Zaabi, Adhari
AU - Alshekaili, Jalila
AU - Al-Khabori, Murtadha
N1 - ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
PY - 2021/9/27
Y1 - 2021/9/27
N2 - Proteomics is the complete evaluation of the function and structure of proteins to understand an organism's nature. Mass spectrometry is an essential tool that is used for profiling proteins in the cell. However, biomarker discovery remains the major challenge of proteomics because of their complexity and dynamicity. Therefore, combining the proteomics approach with genomics and bioinformatics will provide an understanding of the information of biological systems and their disease alteration. However, most studies have investigated a small part of the proteins in the blood. This review highlights the types of proteomics, the available proteomic techniques, and their applications in different research fields.
AB - Proteomics is the complete evaluation of the function and structure of proteins to understand an organism's nature. Mass spectrometry is an essential tool that is used for profiling proteins in the cell. However, biomarker discovery remains the major challenge of proteomics because of their complexity and dynamicity. Therefore, combining the proteomics approach with genomics and bioinformatics will provide an understanding of the information of biological systems and their disease alteration. However, most studies have investigated a small part of the proteins in the blood. This review highlights the types of proteomics, the available proteomic techniques, and their applications in different research fields.
UR - https://www.mendeley.com/catalogue/4fae82d3-d477-3725-adc1-68049ac6e437/
U2 - 10.4331/wjbc.v12.i5.57
DO - 10.4331/wjbc.v12.i5.57
M3 - Review article
C2 - 34630910
SN - 1949-8454
VL - 12
SP - 57
EP - 69
JO - World Journal of Biological Chemistry
JF - World Journal of Biological Chemistry
IS - 5
ER -
