Protein Nutrition in Autism

Saravana Babu Chidambaram; Abid Bhat; Arehally Marappa Mahalakshmi; Bipul Ray; Sunanda Tuladhar; B. S. Sushmitha; B. Saravanan; Manivasagam Thamilarasan; Arokiasamy Justin Thenmozhi; Musthafa Mohamed Essa; Gilles J. Guillemin; M. Walid Qoronfleh

doi:10.1007/978-3-030-30402-7_20

Protein Nutrition in Autism

Saravana Babu Chidambaram^*, Abid Bhat, Arehally Marappa Mahalakshmi, Bipul Ray, Sunanda Tuladhar, B. S. Sushmitha, B. Saravanan, Manivasagam Thamilarasan, Arokiasamy Justin Thenmozhi, Musthafa Mohamed Essa, Gilles J. Guillemin, M. Walid Qoronfleh

^*Corresponding author for this work

Food Science and Nutrition

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Citations (Scopus)

Abstract

Autism is a developmental disorder that affects communication and behavior. Although autism can be diagnosed at any age, it is said to be a “developmental disorder” because symptoms generally appear in the first 2 years of life. The primary cause of autism is still not clear and therapy is currently restricted to controlling behavioral abnormalities. However, emerging studies have shown a link between mitochondrial dysfunction and autism. Dietary supplements that promote mitochondrial biogenesis and inhibit the production of oxidative stress have been used to treat autism patients. Dietary adjustments in treating autism is a novel approach to suppress autistic symptoms. Supplementation with antioxidants has been found to not only inhibit cognitive decline but also improve behavioral symptoms in autism. Dietary supplements fortified with vitamins should only be given under the supervision of a physician. A wide range of nutraceuticals are under clinical trials to understand whether they physiologically target mitochondrial pathways and improve the quality of life in autism.

Original language	English
Title of host publication	Advances in Neurobiology
Publisher	Springer
Pages	573-586
Number of pages	14
DOIs	https://doi.org/10.1007/978-3-030-30402-7_20
Publication status	Published - 2020

Publication series

Name	Advances in Neurobiology
Volume	24
ISSN (Print)	2190-5215
ISSN (Electronic)	2190-5223

Keywords

Amino acids
ASD
Autism
Dietary therapy
Gluten-free, casein-free (GFCF) diet
Malabsorption
Mitochondrial dysfunction
Nutritional imbalance
Peptides
Protein maldigestion

ASJC Scopus subject areas

Biochemistry
Neurology
Developmental Neuroscience
Cellular and Molecular Neuroscience

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10.1007/978-3-030-30402-7_20

Cite this

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abstract = "Autism is a developmental disorder that affects communication and behavior. Although autism can be diagnosed at any age, it is said to be a “developmental disorder” because symptoms generally appear in the first 2 years of life. The primary cause of autism is still not clear and therapy is currently restricted to controlling behavioral abnormalities. However, emerging studies have shown a link between mitochondrial dysfunction and autism. Dietary supplements that promote mitochondrial biogenesis and inhibit the production of oxidative stress have been used to treat autism patients. Dietary adjustments in treating autism is a novel approach to suppress autistic symptoms. Supplementation with antioxidants has been found to not only inhibit cognitive decline but also improve behavioral symptoms in autism. Dietary supplements fortified with vitamins should only be given under the supervision of a physician. A wide range of nutraceuticals are under clinical trials to understand whether they physiologically target mitochondrial pathways and improve the quality of life in autism.",

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AU - Bhat, Abid

AU - Mahalakshmi, Arehally Marappa

AU - Ray, Bipul

AU - Tuladhar, Sunanda

AU - Sushmitha, B. S.

AU - Saravanan, B.

AU - Thamilarasan, Manivasagam

AU - Thenmozhi, Arokiasamy Justin

AU - Essa, Musthafa Mohamed

AU - Guillemin, Gilles J.

AU - Qoronfleh, M. Walid

PY - 2020

Y1 - 2020

N2 - Autism is a developmental disorder that affects communication and behavior. Although autism can be diagnosed at any age, it is said to be a “developmental disorder” because symptoms generally appear in the first 2 years of life. The primary cause of autism is still not clear and therapy is currently restricted to controlling behavioral abnormalities. However, emerging studies have shown a link between mitochondrial dysfunction and autism. Dietary supplements that promote mitochondrial biogenesis and inhibit the production of oxidative stress have been used to treat autism patients. Dietary adjustments in treating autism is a novel approach to suppress autistic symptoms. Supplementation with antioxidants has been found to not only inhibit cognitive decline but also improve behavioral symptoms in autism. Dietary supplements fortified with vitamins should only be given under the supervision of a physician. A wide range of nutraceuticals are under clinical trials to understand whether they physiologically target mitochondrial pathways and improve the quality of life in autism.

AB - Autism is a developmental disorder that affects communication and behavior. Although autism can be diagnosed at any age, it is said to be a “developmental disorder” because symptoms generally appear in the first 2 years of life. The primary cause of autism is still not clear and therapy is currently restricted to controlling behavioral abnormalities. However, emerging studies have shown a link between mitochondrial dysfunction and autism. Dietary supplements that promote mitochondrial biogenesis and inhibit the production of oxidative stress have been used to treat autism patients. Dietary adjustments in treating autism is a novel approach to suppress autistic symptoms. Supplementation with antioxidants has been found to not only inhibit cognitive decline but also improve behavioral symptoms in autism. Dietary supplements fortified with vitamins should only be given under the supervision of a physician. A wide range of nutraceuticals are under clinical trials to understand whether they physiologically target mitochondrial pathways and improve the quality of life in autism.

KW - Amino acids

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KW - Autism

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KW - Gluten-free, casein-free (GFCF) diet

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KW - Mitochondrial dysfunction

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KW - Peptides

KW - Protein maldigestion

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ER -

Protein Nutrition in Autism

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Keywords

ASJC Scopus subject areas

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