Primary gastric yolk sac tumour

Asim Qureshi*, Mansour Al-Moundhri, Maha Al-Shaibi, Ibrahim Al-Haddabi, Alok Mittal

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Primary gastric yolk tumours are extremely rare. We report a 52-year-old male who presented to the Sultan Qaboos University Hospital, Muscat, Oman, in 2017 after having undergone a gastrectomy abroad due to a suspected poorly-differentiated adenocarcinoma. The patient subsequently returned to Oman to receive chemotherapy. However, while undergoing chemotherapy, an abdominal computed tomography scan revealed a lobulated mesenteric mass. Microscopic examination of the resected lesion confirmed a diagnosis of a yolk sac tumour. The mass was diffusely positive for α-fetoprotein (AFP) and a gastric carcinoma stain was negative. Gastrectomy slides from the patient’s previous surgery were examined retrospectively. The morphology was typical for a yolk sac tumour and was negative for epithelial markers. An AFP stain showed diffuse immunoreactivity. Thus, the patient was deemed to have had a primary gastric yolk sac tumour which had later metastasised to the mesocolon. Germ cell tumour protocols were initiated and the patient responded well to treatment.

Original languageEnglish
Pages (from-to)e383-e385
JournalSultan Qaboos University Medical Journal
Issue number3
Publication statusPublished - Aug 2018


  • Case report
  • Diagnostic errors
  • Gastrectomy
  • Germ cell tumor
  • Metastasis
  • Oman
  • Yolk sac tumor

ASJC Scopus subject areas

  • Medicine(all)


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