Porcelain gallbladder: Decoding the malignant truth

Norman O. Machado*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

14 Citations (Scopus)


Gallbladder calcification, also referred to as porcelain gallbladder, has received significant attention in the medical literature due to its perceived role in increasing the risk of developing a gallbladder carcinoma. However, recent reports raise questions challenging this purported high risk. While previous studies reported a concomitant incidence of gallbladder cancer in porcelain gallbladder ranging from 7–60%, more recent analyses indicate the incidence to be much lower (6%). Based on evidence in the current literature, a prophylactic cholecystectomy is not routinely recommended for all patients with porcelain gallbladder and should be restricted to those with conventional indications, such as young patients. However, it is important to note that a nonoperative approach may require prolonged follow-up. A laparoscopic cholecystectomy is a feasible therapeutic option for patients with porcelain gallbladder, although some researchers have indicated a higher incidence of complications and conversion due to technical difficulties.

Original languageEnglish
Pages (from-to)e416-e421
JournalSultan Qaboos University Medical Journal
Issue number4
Publication statusPublished - Nov 2016


  • Carcinomas
  • Cholecystectomy
  • Gallbladder diseases
  • Physiological calcification

ASJC Scopus subject areas

  • General Medicine


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