Persistent gram-negative neurosurgical meningitis in a neonate, successfully treated with intraventricular colistin: Case report and review of the literature: Case Report and Review of the Literature

Laila S Al Yazidi, Brendan McMullan, Saeed Kohan, Pamela Palasanthiran

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


We present a case of Gram-negative neurosurgical meningitis in a neonate, refractory to optimal intravenous therapy and removal of ventriculoperitoneal shunt. Cerebrospinal fluid was sterilized within 24 hours using intraventricular colistin. This is the first report of intraventricular colistin use in neonatal meningitis caused by Enterobacter cloacae.

Original languageUndefined/Unknown
Pages (from-to)e79-e81
JournalThe Pediatric Infectious Disease Journal
Issue number3
Publication statusPublished - 2018


  • Gram-negative neurosurgical meningitis
  • children
  • colistin
  • intraventricular/intrathecal
  • polymyxins

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Pediatrics, Perinatology, and Child Health

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