TY - JOUR
T1 - Overcoming the Odds
T2 - Successful Treatment of Disseminated Mucormycosis with Gastrointestinal and Jaw Involvement in a Patient with Acute Myeloid Leukemia
AU - Al-Busaidi, Thuraya
AU - Al-Bulushi, Fatma
AU - Al-Zadjali, Adil
AU - Bakathir, Abdulaziz
AU - Balkhair, Abdullah
AU - Al Busaidi, Ibrahim
N1 - Copyright © 2023 Thuraya Al-Busaidi et al.
PY - 2023/10/3
Y1 - 2023/10/3
N2 - Disseminated mucormycosis is a rare life-threatening fungal infection that is uniquely seen in severely immunocompromised patients including those with hematological malignancies. We report a case of disseminated mucormycosis with a biopsy-proven gastrointestinal and oral cavity involvement in a patient with acute myeloid leukemia during induction chemotherapy. The patient had a successful outcome with limited resection of the involvement bowel segment, multiple maxillary dental extractions, debridement of the alveolus and hard palate, and combined antifungal therapy. After clinical improvement, stable infection on serial abdominal imaging, and completion of 6 weeks of combined antifungal therapy, consolidation chemotherapy was given, and molecular remission was achieved. The patient remained clinically well on secondary antifungal prophylaxis.
AB - Disseminated mucormycosis is a rare life-threatening fungal infection that is uniquely seen in severely immunocompromised patients including those with hematological malignancies. We report a case of disseminated mucormycosis with a biopsy-proven gastrointestinal and oral cavity involvement in a patient with acute myeloid leukemia during induction chemotherapy. The patient had a successful outcome with limited resection of the involvement bowel segment, multiple maxillary dental extractions, debridement of the alveolus and hard palate, and combined antifungal therapy. After clinical improvement, stable infection on serial abdominal imaging, and completion of 6 weeks of combined antifungal therapy, consolidation chemotherapy was given, and molecular remission was achieved. The patient remained clinically well on secondary antifungal prophylaxis.
UR - https://www.mendeley.com/catalogue/8754538b-e3a1-3a00-b0c6-4f21dd328542/
U2 - 10.1155/2023/5556540
DO - 10.1155/2023/5556540
M3 - Article
C2 - 37822573
SN - 2090-6625
VL - 2023
SP - 1
EP - 5
JO - Case reports in infectious diseases
JF - Case reports in infectious diseases
ER -