Natural products and their benefits on experimental hyperammonemia - a review

Subash Selvaraju, M. Mohamed Essa*, Mostafa I. Waly, Amanat Ali, Amani S. Al-Rawahi, Reshmi K. Vijayan, Gilles J. Guillemin, Subramanian Perumal, Tamilarasan Manivasagam, Annadurai Anandhan

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Natural products (phytochemicals), either as in whole food or as plant extracts,exhibit successful activity against numerous disease targets. Currently no efficienttreatments are available that allow rapid and sustained decrease in blood ammonia levels. Natural plant phytochemicals have been reported to have some anti-hyperammonemicactivity due to their antioxidant potential and removal of excess ammonia. This chapterreviews and discusses the medicinal properties and role of anti-hyperammonemic activityof natural plant phytochemicals such as Momordica charantia, Semecarpus anacardiumnut, Withania somnifera, Pongamia pinnata, Hibiscus sabdariffa, morin, and rutin. Natural products with antioxidant activity may be used to help in preventing a number ofmetabolic disorders and non-communicable diseases including hyperammonemia byreducing oxidative damage.

Original languageEnglish
Title of host publicationFood as Medicine
PublisherNova Science Publishers, Inc.
Number of pages22
ISBN (Print)9781624177477
Publication statusPublished - 2013


  • Hibiscus sabdariffa
  • Hyperammonemia
  • Momordica charantia
  • Morin
  • Pongamia pinnata
  • Rutin
  • Semecarpus anacardium nut
  • Withania somnifera

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences


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