Larvicidal activity of extracts and triterpenoids from Lantana camara

Majekodunmi O. Fatope*, Labaran Salihu, Stephen K. Asante, Yoshio Takeda

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Extracts of the leaves, twigs, stems and roots of Lantana camara Linn. (Verbenaceae) were solvent-partitioned and screened for activity in the brine shrimp lethality test (BST). The active fractions yielded known oleanonic acid (1), lantadene A (2) and oleanolic acid (3), which were very toxic to brine shrimp larvae. Compounds 1-3 were not lethal to Spodoptera littoralis Biosduval (Lepidoptera: Noctuidae), Clavigralla tomentosicollis Stal. (Hemiptera: Coreidae) and Aphis craccivora Koch (Homoptera: Aphididae) when tested at 5000 μg/ml. Compound 2, however, suppressed the fecundity of C. tomentosicollis at this concentration.

Original languageEnglish
Pages (from-to)564-567
Number of pages4
JournalPharmaceutical Biology
Issue number8
Publication statusPublished - Dec 2002


  • Brine shrimp
  • Lantana camara
  • Pest control
  • Triterpenes
  • Verbenaceae

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine


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