Langerhan’s cell histiocytosis of sphenoid sinus causing vision loss: A case report

Suresh Mani*, Regi Thomas, John Mathew, Rajiv Michael

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Langerhan’s cell histiocytosis is an uncontrolled proliferation of dendritic cells. The involvement of skull base is rare. Variable clinical presentation and multi organ involvement often warrant a multidisciplinary approach for a successful diagnosis. We are reporting a case of 16-year-old male with sphenoid sinus Langerhan’s cell histiocytosis which presented as a sudden and painless loss of vision. It is a rare entity in the diagnosis of blindness. Delayed diagnosis and treatment can result in serious complications. The radiological features and management options are discussed with a review of the pertinent literature.

Original languageEnglish
Pages (from-to)281-284
Number of pages4
JournalJournal of the Nepal Medical Association
Issue number218
Publication statusPublished - 2019
Externally publishedYes


  • Blindness
  • Histiocytosis
  • Langerhans-cell
  • Sphenoid sinus

ASJC Scopus subject areas

  • General Medicine


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