Killing of Escherichia coli strains from clinical specimens in human serum and polymorphonuclear leucocytes.

Surinder Kumar*, Meher Rizvi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Hundred Escherichia coli strains were collected from extra-intestinal and intestinal disease for the present study. Of the strains isolated 49 (49%) were serum sensitive and 47 (47%) serum resistant. The remaining 4 (4%) strains showed intermediate sensitivity to the pooled normal human serum (PNHS). Strains isolated from faeces were significantly more sensitive than strains of extra-intestinal origin (P<0.01). Response of Escherichia coli strains to killing by polymorphonuclear leucocytes was seen in 50 isolates (50%). Faecal strains showed significantly more intracellular killing as compared to extra-intestinal strains (P<0.01). Thus, clinical significance of Escherichia coli strains from different sources can be determined by the resistance to the bactericidal effect of human serum and killing in polymorphonuclear leucocytes.

Original languageEnglish
Pages (from-to)173-175
Number of pages3
JournalIndian Journal of Pathology and Microbiology
Issue number2
Publication statusPublished - Apr 2002
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Microbiology (medical)

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