Abstract
Since December 2019, various types of strategies have been applied due to the emergent need to investigate the biology and pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to discover a functional treatment. Different disease modeling systems, such as mini-organ technology, have been used to improve our understanding of SARS-CoV-2 physiology and pathology. During the past 2 years, regenerative medicine research has shown the supportive role of organoid modeling in controlling coronavirus disease 2019 (COVID-19) through optimal drug and therapeutic approach improvement. Here, we overview some efforts that have been made to study SARS-CoV-2 by mimicking COVID-19 using stem cells. In addition, we summarize a perspective of drug development in COVID-19 treatment via organoid-based studies.
Original language | English |
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Article number | 37 |
Journal | Virology Journal |
Volume | 20 |
Issue number | 1 |
DOIs | |
Publication status | Published - Dec 2023 |
Externally published | Yes |
Keywords
- COVID-19
- Organoid
- Regenerative medicine
- SARS-CoV-2
- Stem cell
ASJC Scopus subject areas
- Virology
- Infectious Diseases