Hypomenorrhea in Adolescents and Youths: Normal Variant or Menstrual Disorder? Revision of Literature and Personal Experience

Vincenzo de Sanctis*, Ashraf Soliman, Ploutarchos Tzoulis, Shahina Daar, Salvatore Di Maio, Giuseppe Millimaggi, Christos Kattamis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Menstrual health affects a large number of women throughout reproductive life since adolescence. Knowledge of the duration and variation of the menstrual cycle is necessary for patient education and to identify deviations from normal to guide clinical evaluation. The average duration of menstrual flow is between 4 to 6 days, with anormal range from 2 up to 8 days; the mean blood loss per menstrual cycle is 25-30 mL. In general, descriptive data falling outside the normal range are considered to be indicative of menstrual disorders. Although the American Academy of Pediatricshttps://www.ncbi.nlm.nih.gov/pmc/ articles/PMC5710410/-poi170032r27 and American College of Obstetricians and Gynecologistshttps:// www.ncbi.nlm.nih.gov/pmc/articles/PMC5710410/-poi170032r29 advocate for clinicians to consider the menstrual cycle as a vital sign in adolescents, the identification of subjects with hypomenorrhea is neither well defined nor routinely practiced. In this paper we have summarized the published prevalence of hypomenorrhea (lighter and/or shorter menstrual bleeding) in adolescents and youths in different countries and report the personal experience in four adolescents. (www.actabiomedica.it).

Original languageEnglish
Article numbere2022157
JournalActa Biomedica
Issue number1
Publication statusPublished - Mar 14 2022


  • Adolescents
  • hypomenorrhea
  • menstrual blood loss
  • menstrual disorders
  • menstrual health

ASJC Scopus subject areas

  • Medicine(all)


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