Hepatic Lipidosis Associated with Cobalt Deficiency in Omani Goats

E. H. Johnson*, D. E. Muirhead, K. Annamalai, G. J. King, R. Al-Busaidy, M. Shahul Hameed

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Livers from 36 of 684 (5.3%) apparently healthy goats examined at an abattoir in the greater Muscat area of Oman exhibited gross pathological findings characterized by extremely pale, friable, fatty livers encompassing the entire organ. Histopathologically, diffuse hepatic lipidosis and occasional bile duct proliferation were observed. Periodic acid-Schiff-positive, diastase-resistant pigment was observed in the macrophages lining the sinusoids. These histopathological lesions were consistent with those characteristic of ovine white liver disease. Cobalt analysis revealed that normal livers had six times more cobalt and a 3-fold less fat content than those measured in the fatty livers. This is the first report of an association between cobalt deficiency and hepatic lipidosis in Omani goats.

Original languageEnglish
Pages (from-to)215-221
Number of pages7
JournalVeterinary Research Communications
Issue number4
Publication statusPublished - 1999


  • Cobalt deficiency
  • Fat
  • Goats
  • Lipidosis
  • Liver

ASJC Scopus subject areas

  • General Veterinary


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