Fuzzy Clustering to Asses BALI and LIBRA Factors for Estimation of DTI Measures

Ahmad Akbarifar, Adel Maghsoudpour, Fatemeh Mohammadian, Morteza Mohammadzaheri, Omid Ghaemi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Diffusion magnetic resonance imaging (dMRI) is a popular technique for diagnosing dementia through finding a number of measures with diffusion tensor imaging (DTI). However, this technique is too expensive to be widely used to scan populations. The primary objective of this research is to identify factors/indices which are both (i) rather inexpensive to find, and (ii) usable to estimate DTI measures and eventually to diagnose dementia. This will the basis for a low-cost diagnostic solution. Such factors are selected amongst lifestyle for brain health (LIBRA) and brain atrophy and lesion index (BALI) factors. These factors are pertinent to dementia and relatively inexpensive to find. However, BALI and LIBRA are comprised of 49 factors altogether, and development of a diagnostic algorithm with 49 inputs is infeasible. Therefore, it is necessary to pick the most impactful factors to be used in diagnosis algorithm development. Fuzzy subtractive clustering was employed for this purpose. This research shows that the grey matter lesions and subcortical dilated perivascular spaces (GM-SV) and periventricular white matter lesions (PV) from BALI and age, level of education, job status, antidepressant drugs, diabetes control drugs, obesity (BMI) and dementia preventive diet from LIBRA are the most influential factors to identify DTI measures.

Original languageEnglish
Title of host publicationICAC 2023 - 28th International Conference on Automation and Computing
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1-6
Number of pages6
ISBN (Electronic)9798350335859
ISBN (Print)9798350335859
DOIs
Publication statusPublished - Aug 30 2023
Event28th International Conference on Automation and Computing, ICAC 2023 - Birmingham, United Kingdom
Duration: Aug 30 2023Sept 1 2023

Publication series

NameICAC 2023 - 28th International Conference on Automation and Computing

Conference

Conference28th International Conference on Automation and Computing, ICAC 2023
Country/TerritoryUnited Kingdom
CityBirmingham
Period8/30/239/1/23

Keywords

  • BALI
  • DTI
  • Dementia
  • Diffusion MRI
  • Fuzzy subtractive clustering
  • LIBRA

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computer Science Applications
  • Automotive Engineering
  • Electrical and Electronic Engineering
  • Industrial and Manufacturing Engineering
  • Control and Optimization
  • Modelling and Simulation

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