Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome

Abdul Hakeem Al Hashim*, Ibrahim Al-Zakwani, Abdullah Al Jadidi, Ruqaiya Al Harthi, Maadh Al Naabi, Ramakrishna Biyappu, Sonali Kodange, Naveen Kumar Asati, Tamadher Al Barhi, Mudhun Mohan, Jayachandiran Jagadeesan, Micheline Sachez, Praisemabel S. Sycaayao, Khalfan Al Amrani, Huda Al Khalili, Rashid Al Mamari, Mujahid Al-Busaidi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


OBJECTIVES: This study sought to determine whether early prone positioning of patients with moderate to severe COVID-19-related acute respiratory distress syndrome (ARDS) lowers the mortality rate.

METHODS: We conducted a retrospective study using data from intensive care units of two tertiary centers in Oman. Adult patients with moderate to severe COVID-19-related ARDS with a PaO2/FiO2 ratio < 150 on FiO2 of 60% or more and a positive end-expiratory pressure of at least 8 cm H2O who were admitted between 1 May 2020 and 31 October 2020 were selected as participants. All patients were intubated and subjected to mechanical ventilation within 48 hours of admission and placed in either prone or supine position. Mortality was measured and compared between the patients from the two groups.

RESULTS: A total of 235 patients were included (120 in the prone group and 115 in the supine group). There were no significant differences in mortality (48.3% vs. 47.8%; p =0.938) and discharge rates (50.8% vs. 51.3%; p =0.942) between the prone and supine groups, respectively.

CONCLUSIONS: Early prone positioning of patients with COVID-19-related ARDS does not result in a significant reduction in mortality.

Original languageEnglish
Article numbere465
Pages (from-to)e465
JournalOman Medical Journal
Issue number1
Publication statusPublished - Jan 31 2023


  • COVID-19
  • Oman
  • Positive-Pressure Respiration
  • Prone Position
  • Respiratory Distress Syndrome
  • Retrospective Studies

ASJC Scopus subject areas

  • General Medicine

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