Determinants of health-related quality of life among Omanis hospitalized patients with cancer: a cross-sectional study

Zamzam Al-Habsi, Huda Al-Noumani*, Iman Al Hashmi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


PURPOSE: This study aimed to examine the difference in HRQoL by participants' characteristics and to investigate the determinants of health-related quality of life HRQoL among Omani hospitalized patients with cancer.

METHODS: This cross-sectional study was conducted in two oncology centers in Oman. Omani hospitalized patients with breast, thyroid, colorectal, stomach, and prostate cancer were recruited using convenience sampling. Participants completed Arabic versions of Pittsburgh Sleep Quality Index to measure sleep quality, Brief Fatigue Inventory scales to measure fatigue, and Functional Assessment of Cancer Therapy to measure HRQoL. Descriptive and inferential statistics were performed. T-test, ANOVA, and multiple linear regression analysis were utilized to determine predictors of HRQOL.

RESULTS: In total, 275 participants were recruited (Mean age = 52 years). About 64% of the participates reported poor sleep and 18.5% reported severe cancer-related fatigue. Younger patients who had good sleep quality and less cancer-related fatigue and had prostate and thyroid cancer demonstrated better HRQoL [F (5, 269) = 26.26, p < 0.000]. The model explained 33% of the variances in the HRQoL (R 2  = .328).

CONCLUSIONS: This study highlights the impact of age, cancer type, sleep quality, and cancer-related fatigue on the HRQoL in hospitalized patients with cancer. Thus, sleep quality and cancer-related fatigue should be assessed routinely during the hospitalization of oncology patients with unique attention to patients' age and cancer type.

Original languageEnglish
Pages (from-to)2061-2070
Number of pages10
JournalQuality of Life Research
Issue number7
Publication statusPublished - Jan 23 2022


  • Cross-Sectional Studies
  • Fatigue
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Prostatic Neoplasms
  • Quality of Life/psychology
  • Surveys and Questionnaires


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