Dengue fever complicated by hemophagocytosis

Maria Koshy*, Ajay Kumar Mishra, Bhumi Agrawal, Akhil Rajendra Kurup, Samuel George Hansdak

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

13 Citations (Scopus)


Dengue is acommon acute viral febrile illness in the tropics. Although the usual presentation is that of a self-limiting illness, its complications are protean. We report a 29-year-old man who presented with an acute febrile illness and was diagnosed with dengue hemorrhagic fever. Despite appropriate supportive therapy, the patient initially improved, but subsequently had clinical deterioration. Evaluation revealed features of hemophagocytic lymphohistiocytosis. He was successfully treated with glucocorticoids and had an uneventful recovery. This case adds to the limited adult cases of virus-associated hemophagocytic syndrome in the literature and the need for prompt recognition and treatment of this rare complication.

Original languageEnglish
Pages (from-to)121-124
Number of pages4
JournalOxford Medical Case Reports
Issue number6
Publication statusPublished - Jan 2016
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Infectious Diseases


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