Coronavirus disease 2019 (Covid-19) in adolescents: An update on current clinical and diagnostic characteristics

Vincenzo De Sanctis*, Leopoldo Ruggiero, Ashraf T. Soliman, Shahina Daar, Salvatore Di Maio, Christos Kattamis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Summary. The current outbreak of infections with SARS-CoV-2 is defined as Coronavirus Disease 2019 (COVID-19). The clinical symptoms of COVID-19 include fever, fatigue, cough, breathing difficulty that may lead to respiratory distress; a small population of patients may have diarrhea, nausea or vomiting. The highest infection rate occurs in adults; however, neonates, children, and adolescents can also be infected. As the outbreak continues to spread worldwide, attention has switched toward determinants of clinical manifestations and disease severity. The situation surrounding the outbreak is rapidly evolving and the information and recommendations are changing as new information becomes available. This paper summarises the current findings (April 3,2020) from a systematic literature review on the current knowledge of COVID-19 in adolescents (10-19 years according to the WHO definition) and reports the preliminary epidemiological data stated by the Italian National Institute of Health. (

Original languageEnglish
Pages (from-to)184-194
Number of pages11
JournalActa Biomedica
Issue number2
Publication statusPublished - 2020


  • Adolescents
  • COVID-19
  • Children
  • Clinical and diagnostic characteristics
  • Coronavirus Disease 2019

ASJC Scopus subject areas

  • General Medicine


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