Brain blood flow abnormalities associated with oral cocaine use

Bankole Johnson*, Lamk Lamki, Bruce Barron, Ralph Spiga, Richard Chen, Richard Meisch, Neera Khilnani

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Single photon emission tomography (SPECT) is the prototypical tool for measuring cerebral blood flow (CBF) in discrete areas of the brain. Compared with when a male 'crack' cocaine user received placebo, oral cocaine (1 mg/kg) ingestion was associated with non-uniformity of overall CBF with hypoperfusion of discrete brain regions, particularly of the frontal, temporo-parietal, basal ganglia, and thalamic areas. While these results should be viewed as preliminary, they do suggest that oral cocaine use may be associated with CBF abnormalities in 'crack' users.

Original languageEnglish
Pages (from-to)72-73
Number of pages2
JournalIrish Journal of Psychological Medicine
Issue number2
Publication statusPublished - 1997
Externally publishedYes


  • Brain
  • Cerebral blood flow
  • Neuroimaging
  • Oral cocaine
  • Tc-HMPAO

ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health
  • History and Philosophy of Science


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