Bioactive metabolites in improved cowpea seeds

O. M. Ameen*, O. M. Fatope, L. A. Usman, S. A. Adebayo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The International Institute of Tropical Agriculture (IITA) has developed some pest and disease resistant cowpeas. From these the seeds of 8 cowpea cultivars were extracted with ethanol, and partitioned into chloroform and water-soluble fractions, the water-soluble fraction was further extracted with ethyl acetate. Residues from ethanol, chloroform and ethyl acetate soluble fractions for each of the 8 cowpea cultivars were screened against brine shrimp larvae. The seed extracts of cowpea cultivars IT93K - 596 - 9 - 12, IT90K - 277 - 2 and IT93K - 452 - 1 were found to be most active, indicating that they contain cytotoxic compound(s).

Original languageEnglish
Pages (from-to)513-516
Number of pages4
JournalAfrican Journal of Biotechnology
Issue number6
Publication statusPublished - Jun 2005


  • Bioactive compund
  • Biotechnology
  • Brine shrimp larvae
  • Cowpea
  • Cytotoxicity

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Genetics
  • Agronomy and Crop Science


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