Abstract
Choriocarcinoma (CC) is a malignant neoplasm of the trophoblastic tissue, with a potential to metastasise to distant organs. Limited case of gestational CC develops after a long latent period. We report a 52-year-old postmenopausal woman who developed metastatic choriocarcinoma presumably of gestational origin, 8 years after the last pregnancy and 2 years after the last menstrual period. The patient was brought to the emergency room of a tertiary care centre in Muscat, Oman, in 2022 and was diagnosed with CC metastatic to the brain, spleen, lung and the kidney. The β-human chorionic gonadotrophin level was found to be raised (1,292,867 mIU/mL). The International Federation of Gynecologic Oncology risk score was calculated to be 14 (very high risk). The patient was initially treated with whole-brain radiotherapy and splenic artery embolisation because of a hemoperitoneum. Afterwards the patient received systemic treatment using the standard EMA/CO regimen till complete serological remission.
Original language | English |
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Pages (from-to) | 135-138 |
Number of pages | 4 |
Journal | Sultan Qaboos University Medical Journal |
Volume | 24 |
Issue number | 1 |
DOIs | |
Publication status | Published - Feb 28 2024 |
Externally published | Yes |
Keywords
- Brain
- Choriocarcinoma
- Latency Period
- Oman
- Postmenopause
- Emergency Service, Hospital
- Hemoperitoneum
- Humans
- Middle Aged
- Embolization, Therapeutic
- Pregnancy
- Choriocarcinoma/diagnosis
- Female
ASJC Scopus subject areas
- General Medicine