4’-methyl-2’-(Quinolin-8-ylcarbamoyl)-biphenyl-4-carboxylic acid ethyl ester

Hamad H. Al Mamari*, Anfal Al Hasani

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

1 Citation (Scopus)


In this short note communication, we report the synthesis of a novel amide 4’-methyl-2’-(quinolin-8-ylcarbamoyl)-biphenyl-4-carboxylic acid ethyl ester by the Ru-catalyzed C(sp2)-H bond arylation reaction. The catalytic C-H bond functionalization reaction was employed, amongst other reaction reagents and conditions, [RuCl2(p-cymene)]2 as a precatalyst and (p-tol)3P as a ligand. The arylation product was characterized by various spectroscopic methods (1H NMR,13C NMR, IR, GC-MS, and IR spectroscopy), and its composition was confirmed by elemental analysis.

Original languageEnglish
Article numberM1132
Issue number2
Publication statusPublished - May 2020


  • Benzamides
  • Bidentate directing groups
  • C-H bond functionalization
  • Catalysis
  • Chelation assistance
  • Organic synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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