Treatment of renal stones with frankincense (Boswellic acid)

Frankincense, or olibanum, is the oleogum resin that is harvested from several different trees, an aromatic resin obtained from trees of the genus Boswellia. The word frankincense is derived from the ancient French name ?frankincense,? meaning ?pure incense.? Frankincense is also known in Arabic as ?luban,?. Luban has been reported to have anti-inflammatory, sedative, antibacterial, and anti-cancer activities. The aim of the present study is to treat renal stones with Luban (Boswellia) given as capsules of active oils. This is a clinical single-blind randomized trial, where 100 patients with renal stones (50 Radiopaque and 50 Radiolucent stones) will be included in the study and divided between two treatment groups: Standard treatment (Potassium Citrate/ Uralyt-U) and new treatment (Luban). Patients with stone size less than 10 mm will be include; and patients with renal pathology or comorbidities (DM, CKD, multiple renal cysts, renal tumors) will be excluded. The outcome measures of the study will be: the primary end point (effect) is reduction of stone size by 50% or complete disappearance after 2 years of treatment; and the secondary end point (toxicity) is the patient intolerance of the treatment or development of side effects. If this study proves an effect of Luban on renal stones it will be an evolution in the management of renal stones by a simple, harmless easily available method.