ملخص
(matrix presented) epi-7-Deoxypancratistatin containing the cis-fused phenanthridone core was synthesized in 12 steps from bromobenzene. Key features of this synthesis include the enzymatic oxidation of bromobenzene with toluene dioxygenase, selective opening of a cyclic sulfate over an aziridine with oxygen nucleophiles, and an intramolecular Lewis acid-catalyzed cyclization onto an epoxy conduramine derived via aza-Payne rearrangement.
| اللغة الأصلية | English |
|---|---|
| الصفحات (من إلى) | 115-117 |
| عدد الصفحات | 3 |
| دورية | Organic Letters |
| مستوى الصوت | 4 |
| رقم الإصدار | 1 |
| المعرِّفات الرقمية للأشياء | |
| حالة النشر | Published - يناير 10 2002 |
ASJC Scopus subject areas
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