Recurrent epidemic cycles in an infectious disease model with a time delay in loss of vaccine immunity

D. Greenhalgh*, Q. J.A. Khan, F. I. Lewis

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةArticleمراجعة النظراء

17 اقتباسات (Scopus)

ملخص

In this paper we look at an SIRS epidemiological model with vaccination. Although immunity gained by experiencing the disease is permanent, vaccine-induced immunity is only temporary and a fixed time after vaccination individuals return to the susceptible class. The model is described and equilibrium and stability results are shown. There are three possible equilibria: one where the population is extinct; a disease-free equilibrium where the population is at a steady level and a unique endemic equilibrium. Simulation confirms that although Hopf bifurcation is theoretically possible for realistic parameter values the simulations approach the unique endemic equilibrium.

اللغة الأصليةEnglish
الصفحات (من إلى)e779-e788
دوريةNonlinear Analysis, Theory, Methods and Applications
مستوى الصوت63
رقم الإصدار5-7
المعرِّفات الرقمية للأشياء
حالة النشرPublished - نوفمبر 30 2005

ASJC Scopus subject areas

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