Preparation, structure and spasmolytic activities of some derivatives of harmine series of alkaloids

Sabira Begum*, Syed Imran Hassan, Bina S. Siddiqui, Rehana Ifzal, Sobiya Perwaiz, Tahira Kiran, Farhana Shaheen, M. Nabeel Ghayur, Anwar H. Gilani

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةArticleمراجعة النظراء

6 اقتباسات (Scopus)

ملخص

Keeping in view the interesting chemistry and pharmacological importance of harmine series of bases - the β-carboline alkaloids, a number of new derivatives of tetrahydroharmine (1) and harmalol (2) have been prepared and characterized through spectral studies. Some of these derivatives showed spasmolytic activity. It was observed that all the N -acyl tetrahydroharmine derivatives are stable, not labile and no ring opening occurs in these compounds, as reported recently.

اللغة الأصليةEnglish
الصفحات (من إلى)213-227
عدد الصفحات15
دوريةNatural Product Research
مستوى الصوت20
رقم الإصدار3
المعرِّفات الرقمية للأشياء
حالة النشرPublished - مارس 2006
منشور خارجيًانعم

ASJC Scopus subject areas

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