TY - JOUR
T1 - New-Onset Diabetes Mellitus in COVID-19
T2 - A Scoping Review
AU - The CArdiometabolic Panel of International experts on Syndemic COvid-19 (CAPISCO)
AU - Pantea Stoian, Anca
AU - Bica, Ioana Cristina
AU - Salmen, Teodor
AU - Al Mahmeed, Wael
AU - Al-Rasadi, Khalid
AU - Al-Alawi, Kamila
AU - Banach, Maciej
AU - Banerjee, Yajnavalka
AU - Ceriello, Antonio
AU - Cesur, Mustafa
AU - Cosentino, Francesco
AU - Firenze, Alberto
AU - Galia, Massimo
AU - Goh, Su Yen
AU - Janez, Andrej
AU - Kalra, Sanjay
AU - Kapoor, Nitin
AU - Kempler, Peter
AU - Lessan, Nader
AU - Lotufo, Paulo
AU - Mikhailidis, Dimitri P.
AU - Nibali, Luigi
AU - Papanas, Nikolaos
AU - Powell-Wiley, Tiffany
AU - Rizvi, Ali A.
AU - Sahebkar, Amirhossein
AU - Santos, Raul D.
AU - Toth, Peter P.
AU - Viswanathan, Vijay
AU - Rizzo, Manfredi
N1 - Publisher Copyright:
© 2023, The Author(s).
PY - 2023/9/26
Y1 - 2023/9/26
N2 - Introduction: The coronavirus disease 2019 (COVID-19) pandemic became superimposed on the pre-existing obesity and diabetes mellitus (DM) pandemics. Since COVID-19 infection alters the metabolic equilibrium, it may induce pathophysiologic mechanisms that potentiate new-onset DM, and we evaluated this issue. Method: A systematic review of the literature published from the 1 January 2020 until the 20 July 2023 was performed (PROSPERO registration number CRD42022341638). We included only full-text articles of both human clinical and randomized controlled trials published in English and enrolling adults (age > 18 years old) with ongoing or preceding COVID-19 in whom hyperglycemia was detected. The search was based on the following criteria: “(new-onset diabetes mellitus OR new-onset DM) AND (COVID-19) AND adults”. Results: Articles on MEDLINE (n = 70) and the Web of Science database (n = 16) were included and analyzed by two researchers who selected 20 relevant articles. We found evidence of a bidirectional relationship between COVID-19 and DM. Conclusions: This link operates as a pathophysiological mechanism supported by epidemiological data and also by the clinical and biological findings obtained from the affected individuals. The COVID-19 pandemic raised the incidence of DM through different pathophysiological and psychosocial factors.
AB - Introduction: The coronavirus disease 2019 (COVID-19) pandemic became superimposed on the pre-existing obesity and diabetes mellitus (DM) pandemics. Since COVID-19 infection alters the metabolic equilibrium, it may induce pathophysiologic mechanisms that potentiate new-onset DM, and we evaluated this issue. Method: A systematic review of the literature published from the 1 January 2020 until the 20 July 2023 was performed (PROSPERO registration number CRD42022341638). We included only full-text articles of both human clinical and randomized controlled trials published in English and enrolling adults (age > 18 years old) with ongoing or preceding COVID-19 in whom hyperglycemia was detected. The search was based on the following criteria: “(new-onset diabetes mellitus OR new-onset DM) AND (COVID-19) AND adults”. Results: Articles on MEDLINE (n = 70) and the Web of Science database (n = 16) were included and analyzed by two researchers who selected 20 relevant articles. We found evidence of a bidirectional relationship between COVID-19 and DM. Conclusions: This link operates as a pathophysiological mechanism supported by epidemiological data and also by the clinical and biological findings obtained from the affected individuals. The COVID-19 pandemic raised the incidence of DM through different pathophysiological and psychosocial factors.
KW - Coronavirus disease 2019
KW - Diabetes mellitus
KW - Hyperglycemia
KW - New-onset diabetes
KW - New-onset hyperglycemia
KW - Newly diagnosed diabetes
KW - Prediabetes
KW - Severe acute respiratory syndrome coronavirus-2 infection
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UR - https://www.mendeley.com/catalogue/66f7f242-b7be-3b8d-ab53-73bbf002120f/
U2 - 10.1007/s13300-023-01465-7
DO - 10.1007/s13300-023-01465-7
M3 - Review article
C2 - 37751143
AN - SCOPUS:85172194290
SN - 1869-6953
VL - 15
SP - 33
EP - 60
JO - Diabetes Therapy
JF - Diabetes Therapy
IS - 1
ER -