Neuroprotective effect of natural products against Alzheimer's disease

Musthafa M. Essa, Reshmi K. Vijayan, Gloria Castellano-Gonzalez, Mustaq A. Memon, Nady Braidy, Gilles J. Guillemin*

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةReview articleمراجعة النظراء

217 اقتباسات (Scopus)


Nature has gifted mankind with a plethora of flora-bearing fruits, vegetables and nuts. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease and other neuronal dysfunctions. Accumulated evidence suggests that naturally occurring phyto-compounds, such as polyphenolic antioxidants found in fruits, vegetables, herbs and nuts, may potentially hinder neurodegeneration, and improve memory and cognitive function. Nuts such as walnut have also demonstrated neuroprotective effect against AD. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signalling pathways associated with protein folding and neuroinflammation. The neuroprotective effects of various naturally occurring compounds in AD is evaluating in this review.

اللغة الأصليةEnglish
الصفحات (من إلى)1829-1842
عدد الصفحات14
دوريةNeurochemical Research
مستوى الصوت37
رقم الإصدار9
المعرِّفات الرقمية للأشياء
حالة النشرPublished - سبتمبر 2012
منشور خارجيًانعم

ASJC Scopus subject areas

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