TY - JOUR
T1 - N-(2-hydroxy-1,1-dimethylethyl)-3-methylbenzamide
AU - Al Mamari, Hamad H.
AU - Al Lawati, Yousuf
N1 - Publisher Copyright:
© 2019 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2020/3
Y1 - 2020/3
N2 - The title compound, N-(2-hydroxy-1,1-dimethylethyl)-3-methylbenzamide was synthesized by reacting 3-methylbenzoyl chloride or 3-methylbenzoic acid with 2-amino-2-methyl-1-propanol. In the present report, the synthesized target compound was fully characterized by various spectroscopic methods (1H NMR,13C NMR, IR, GC-MS), its composition confirmed by elemental analysis, and its structure determined and confirmed by X-ray analysis. The importance of this compound lies in its possession of an N,O-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C–H bond functionalization reactions.
AB - The title compound, N-(2-hydroxy-1,1-dimethylethyl)-3-methylbenzamide was synthesized by reacting 3-methylbenzoyl chloride or 3-methylbenzoic acid with 2-amino-2-methyl-1-propanol. In the present report, the synthesized target compound was fully characterized by various spectroscopic methods (1H NMR,13C NMR, IR, GC-MS), its composition confirmed by elemental analysis, and its structure determined and confirmed by X-ray analysis. The importance of this compound lies in its possession of an N,O-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C–H bond functionalization reactions.
KW - Benzamides
KW - Bidentate directing groups
KW - Bis-chelates
KW - C
KW - Chelation assistance
KW - H bond functionalization
KW - Organic synthesis
KW - X-ray structure determination
UR - http://www.scopus.com/inward/record.url?scp=85077257746&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85077257746&partnerID=8YFLogxK
U2 - 10.3390/M1099
DO - 10.3390/M1099
M3 - Article
AN - SCOPUS:85077257746
SN - 1422-8599
VL - 2020
JO - MolBank
JF - MolBank
IS - 1
M1 - M1099
ER -