TY - JOUR
T1 - Idiopathic acute onset myelopathy in cheetah (Acinonyx jubatus) cubs
AU - Walzer, Christian
AU - Url, Angelika
AU - Robert, Nadia
AU - Kübber-Heiss, Anna
AU - Nowotny, Norbert
AU - Schmidt, Peter
PY - 2003/3
Y1 - 2003/3
N2 - Numerous cases of ataxia, hind limb paresis, and paralysis have occurred in cheetah (Acinonyx jubatus) cubs over the past 10 yr within the European Endangered Species Program population, including 12 in mainland Europe, two in the British Isles, one in Namibia, and one in Dubai. The condition is the most important medical factor limiting European cheetah population growth. Eight cubs at the Salzburg Zoo, Austria, were affected. They demonstrated upper motor neuron lesions when alive and bilateral, symmetrical myelin degeneration of the spinal cord on necropsy. Ballooning of myelin sheaths surrounded mostly preserved axons, and no spheroids, characteristic of acute axonal degeneration, were found. Myelin loss markedly exceeded axonal degeneration. The syndrome's etiology is unclear, although viral, bacterial, parasitic, genetic, nutritional-metabolic, toxic, and physical causes have been considered.
AB - Numerous cases of ataxia, hind limb paresis, and paralysis have occurred in cheetah (Acinonyx jubatus) cubs over the past 10 yr within the European Endangered Species Program population, including 12 in mainland Europe, two in the British Isles, one in Namibia, and one in Dubai. The condition is the most important medical factor limiting European cheetah population growth. Eight cubs at the Salzburg Zoo, Austria, were affected. They demonstrated upper motor neuron lesions when alive and bilateral, symmetrical myelin degeneration of the spinal cord on necropsy. Ballooning of myelin sheaths surrounded mostly preserved axons, and no spheroids, characteristic of acute axonal degeneration, were found. Myelin loss markedly exceeded axonal degeneration. The syndrome's etiology is unclear, although viral, bacterial, parasitic, genetic, nutritional-metabolic, toxic, and physical causes have been considered.
KW - Acinonyx jubatus, demyelination
KW - CNS
KW - Cheetah
KW - Copper
KW - Myelopathy
KW - Neurologic disease
KW - Pathology
UR - http://www.scopus.com/inward/record.url?scp=0038605512&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038605512&partnerID=8YFLogxK
U2 - 10.1638/1042-7260(2003)34[0036:IAOMIC]2.0.CO;2
DO - 10.1638/1042-7260(2003)34[0036:IAOMIC]2.0.CO;2
M3 - Article
C2 - 12723798
AN - SCOPUS:0038605512
SN - 1042-7260
VL - 34
SP - 36
EP - 46
JO - Journal of Zoo and Wildlife Medicine
JF - Journal of Zoo and Wildlife Medicine
IS - 1
ER -