TY - JOUR
T1 - Genome-wide analysis and transcriptional regulation of the typical and atypical thioredoxins in Arabidopsis thaliana
AU - Chibani, Kamel
AU - Pucker, Boas
AU - Dietz, Karl-Josef
AU - Cavanagh, Amanda
N1 - © 2021 Federation of European Biochemical Societies.
PY - 2021/11
Y1 - 2021/11
N2 - Thioredoxins (TRXs), a large subclass of ubiquitous oxidoreductases, are involved in thiol redox regulation. Here, we performed a comprehensive analysis of TRXs in the Arabidopsis thaliana genome, revealing 41 genes encoding 18 typical and 23 atypical TRXs, and 6 genes encoding thioredoxin reductases (TRs). The high number of atypical TRXs indicates special functions in plants that mostly await elucidation. We identified an atypical class of thioredoxins called TRX-c in the genomes of photosynthetic eukaryotes. Localized to the chloroplast, TRX-c displays atypical CPLC, CHLC and CNLC motifs in the active sites. In silico analysis of the transcriptional regulations of TRXs revealed high expression of TRX-c in leaves and strong regulation under cold, osmotic, salinity and metal ion stresses.
AB - Thioredoxins (TRXs), a large subclass of ubiquitous oxidoreductases, are involved in thiol redox regulation. Here, we performed a comprehensive analysis of TRXs in the Arabidopsis thaliana genome, revealing 41 genes encoding 18 typical and 23 atypical TRXs, and 6 genes encoding thioredoxin reductases (TRs). The high number of atypical TRXs indicates special functions in plants that mostly await elucidation. We identified an atypical class of thioredoxins called TRX-c in the genomes of photosynthetic eukaryotes. Localized to the chloroplast, TRX-c displays atypical CPLC, CHLC and CNLC motifs in the active sites. In silico analysis of the transcriptional regulations of TRXs revealed high expression of TRX-c in leaves and strong regulation under cold, osmotic, salinity and metal ion stresses.
KW - Arabidopsis
KW - Chloroplasts
KW - Gene Expression Regulation, Plant
KW - Photosynthesis
KW - Thioredoxins
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UR - http://www.scopus.com/inward/citedby.url?scp=85116773129&partnerID=8YFLogxK
U2 - 10.1002/1873-3468.14197
DO - 10.1002/1873-3468.14197
M3 - Article
C2 - 34561866
SN - 0014-5793
VL - 595
SP - 2715
EP - 2730
JO - FEBS Letters
JF - FEBS Letters
IS - 21
ER -