FeS₂ nanosheets–H₂O₂–NaHCO₃ chemiluminescence method for procaine hydrochloride determination

FeS₂ nanosheets (NSs) were produced and exploited as a new catalyst for a chemiluminescence (CL) reaction. The characterization of FeS₂ NSs was performed using spectroscopic methods. In this regard, transmission electron microscopy images showed that FeS₂ NSs have a length of ~0.5–1 μm. The direct optical band gap energy of FeS₂ NSs was found to be 3.45 eV. Prepared FeS₂ NSs were used to catalyze the NaHCO₃–H₂O₂ CL reaction. It was found that procaine hydrochloride (PCH) could reduce the intensity of the FeS₂ NSs–NaHCO₃–H₂O₂ CL reaction so, with increasing PCH concentrations, the intensity of light emission decreased. Therefore, a simple and sensitive method was introduced to measure PCH with a linear range expanded from 1.00 × 10⁻⁶ to 1.00 × 10⁻³ mol L⁻¹ and an 8.32 × 10⁻⁷ mol L⁻¹ limit of detection. Studies related to the effect of foreign species and reaction mechanisms were performed. The application of the approach was verified by quantifying the PCH in the injection.