Evaluation of Cardiac Function in Iron Deficiency Anemia Before and After Total Dose Iron Therapy

J. F. Alvares*, J. L. Oak, A. V. Pathare

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةArticleمراجعة النظراء

11 اقتباسات (Scopus)


Objective : To evaluate the cardiac function before and after the total dose iron therapy (TDI) and to correlate the myocardial function to the rise in haemoglobin after TDI in patients of iron deficiency anemia. Methods : The study included 30 patients of iron deficiency anemia who presented to our institution in the last one year. There were 11 men and 19 women with the mean age of 30 years. Parameters compared before and after TDI infusion included clinical features, haemoglobin, electrocardiogram (ECG), treadmill stress test (TST) and 2 dimensional echocardiogram (2D echo). Results : During the study period 30 patients (11 men and 19 women) were included for TDI. The mean haemoglobin level increased from 5 gm/dl to 5.7 gm/dl 4 days after TDI. The congestive cardiac failure disappeared in four out of eight patients after TDI. The mean heart rate on the ECG pretherapy was 102.66 ± 14.9 and post therapy 93.4 ± 14.9 (p = 0.011). The TST results showed improvement in effort tolerance in 17 out of 24 patients (p= 0.0012) and it improved much before there was a significant rise in haemoglobin. Conclusion : Impaired ventricular performance is observed in patients with iron deficiency anemia. After TDI the left ventricular function improved before there was a significant rise in haemoglobin level proving the theory that correction of the electrophysiological abnormalities of the heart in iron deficiency patient by TDI may be the result of correction of iron at the tissue level.

اللغة الأصليةEnglish
الصفحات (من إلى)204-206
عدد الصفحات3
دوريةJournal of Association of Physicians of India
مستوى الصوت48
رقم الإصدار2
حالة النشرPublished - فبراير 2000
منشور خارجيًانعم

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