TY - JOUR
T1 - Early onset colorectal cancer
T2 - Challenges across the cancer care continuum
AU - AlZaabi, Adhari
AU - AlHarrasi, Amna
AU - AlMusalami, Atika
AU - AlMahyijari, Nawal
AU - Al Hinai, Khalid
AU - ALAdawi, Humaid
AU - Al-Shamsi, Humaid O.
N1 - Funding Information:
This work was supported by SQU Deanship of research fund and Burjeel Medical City .
Publisher Copyright:
© 2022 The Authors
PY - 2022/10
Y1 - 2022/10
N2 - Early Onset Colorectal cancer (EOCRC) incidence is increasing at an alarming pace. An increase of 90% in colon cancer and 124% in rectal cancer is expected by 2030. Patients with EOCRC are not receiving additional attention compared to older patients despite having a unique molecular pattern, majority of cases are sporadic, and related short- and long-term treatment and disease complications. The current management and screening guidelines have been constructed from studies on late onset CRC. Plethora of studies are ongoing to understand this disease entity in order to construct a tailored prevention, detection and management plans. While waiting for a better understanding of the disease, efforts should be directed toward improving the quality of care across the cancer continuum. Here we aim to address the challenges faced by EOCRC patients across the cancer continuum. This will facilitate directing future efforts and research toward construction of a personalized and precise guidelines.
AB - Early Onset Colorectal cancer (EOCRC) incidence is increasing at an alarming pace. An increase of 90% in colon cancer and 124% in rectal cancer is expected by 2030. Patients with EOCRC are not receiving additional attention compared to older patients despite having a unique molecular pattern, majority of cases are sporadic, and related short- and long-term treatment and disease complications. The current management and screening guidelines have been constructed from studies on late onset CRC. Plethora of studies are ongoing to understand this disease entity in order to construct a tailored prevention, detection and management plans. While waiting for a better understanding of the disease, efforts should be directed toward improving the quality of care across the cancer continuum. Here we aim to address the challenges faced by EOCRC patients across the cancer continuum. This will facilitate directing future efforts and research toward construction of a personalized and precise guidelines.
KW - Adolescence and young adult
KW - Early onset colorectal cancer
KW - Palliative care
KW - Prevention
KW - Screening
KW - Survivorship
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U2 - 10.1016/j.amsu.2022.104453
DO - 10.1016/j.amsu.2022.104453
M3 - Review article
C2 - 36268309
AN - SCOPUS:85138062948
SN - 2049-0801
VL - 82
JO - Annals of Medicine and Surgery
JF - Annals of Medicine and Surgery
M1 - 104453
ER -