TY - JOUR
T1 - Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East
AU - Rajan, Rajesh
AU - Jarallah, Mohammed Al
AU - Al-Zakwani, Ibrahim
AU - Dashti, Raja
AU - Sulaiman, Kadhim
AU - Panduranga, Prashanth
AU - Brady, Peter A.
AU - Kobalava, Zhanna
N1 - Publisher Copyright:
Copyright © 2023, Oman Medical Journal.
PY - 2023/7/31
Y1 - 2023/7/31
N2 - Objectives: The Rajan’s heart failure (R-hf) score was proposed to aid risk stratification in heart failure patients. The aim of this study was to validate R-hf risk score in patients with acute decompensated heart failure. Methods: R-hf risk score is derived from the product estimated glomerular filtration rate (mL/min), left ventricular ejection fraction (%), and hemoglobin levels (g/dL) divided by N-terminal pro-brain natriuretic peptide (pg/mL). This was a multinational, multicenter, prospective registry of heart failure from seven countries in the Middle East. Univariable and multivariable logistic regression was applied. Results: A total of 776 patients (mean age = 62.0±14.0 years, 62.4% males; mean left ventricular ejection fraction = 33.0±14.0%) were included. Of these, 459 (59.1%) presented with acute decompensated chronic heart failure. The R-hf risk score group (≤ 5) was marginally associated with a higher risk of all-cause cumulative mortality at three months (adjusted odds ratio (aOR) = 4.28; 95% CI: 0.90–20.30; p = 0.067) and significantly at 12 months (aOR = 3.84; 95% CI: 1.23–12.00; p = 0.021) when compared to those with the highest R score group (≥ 50). Conclusions: Lower R-hf risk scores are associated with increased risk of all-cause cumulative mortality at three and 12 months.
AB - Objectives: The Rajan’s heart failure (R-hf) score was proposed to aid risk stratification in heart failure patients. The aim of this study was to validate R-hf risk score in patients with acute decompensated heart failure. Methods: R-hf risk score is derived from the product estimated glomerular filtration rate (mL/min), left ventricular ejection fraction (%), and hemoglobin levels (g/dL) divided by N-terminal pro-brain natriuretic peptide (pg/mL). This was a multinational, multicenter, prospective registry of heart failure from seven countries in the Middle East. Univariable and multivariable logistic regression was applied. Results: A total of 776 patients (mean age = 62.0±14.0 years, 62.4% males; mean left ventricular ejection fraction = 33.0±14.0%) were included. Of these, 459 (59.1%) presented with acute decompensated chronic heart failure. The R-hf risk score group (≤ 5) was marginally associated with a higher risk of all-cause cumulative mortality at three months (adjusted odds ratio (aOR) = 4.28; 95% CI: 0.90–20.30; p = 0.067) and significantly at 12 months (aOR = 3.84; 95% CI: 1.23–12.00; p = 0.021) when compared to those with the highest R score group (≥ 50). Conclusions: Lower R-hf risk scores are associated with increased risk of all-cause cumulative mortality at three and 12 months.
KW - Arabia
KW - Chronic Kidney Diseases
KW - Heart Failure
KW - Mortality
KW - Ventricular Dysfunction, Left
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UR - https://www.mendeley.com/catalogue/75e895bb-d8eb-37cf-a9cd-013074add5fe/
U2 - 10.5001/omj.2023.89
DO - 10.5001/omj.2023.89
M3 - Article
C2 - 37674520
AN - SCOPUS:85171454795
SN - 1999-768X
VL - 38
JO - Oman Medical Journal
JF - Oman Medical Journal
IS - 4
M1 - e529
ER -