TY - JOUR
T1 - Clinical Predictors of Depression among Patients with Inflammatory Bowel Diseases
T2 - A Cross-sectional Analytical Study from Oman
AU - Al-Aamri, Harith
AU - Al-Huseini, Salim
AU - Chan, Moon Fai
AU - Al Saadi, Alkhatib
AU - Al-Sibani, Nasser
AU - Al-Dughaishi, Zainab
AU - Al-Alawi, Mohammed
N1 - The OMJ is Published Bimonthly and Copyrighted 2022 by the OMSB.
PY - 2022/3/22
Y1 - 2022/3/22
N2 - OBJECTIVES: Many studies suggest that depression is prevalent among patients suffering from inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Both depression and IBD have a significant disease burden. However, these studies have mostly been conducted among European and American populations and there is a paucity of studies from Arab countries. This study aimed to examine the prevalence and predictors of depressive symptoms among adult IBD patients attending a tertiary care hospital in Muscat, Oman.METHODS: We conducted a cross-sectional study among a random sample of patients aged ≥ 18 years who attended the gastroenterology clinic at Sultan Qaboos University Hospital, Muscat, Oman, between June 2018 and January 2019. Participants were asked to complete the Patient Health Questionnaire-9, which is used to assess depression, and a sociodemographic survey. Logistic regression analysis was used to identify the independent predictors of depressive symptoms among the study sample. Adjusted odds ratios (aORs) were also reported.RESULTS: This study included 201 participants, with an average age of 36 years. Just over half (51.2%) of participants were female. The mean duration of the patients' IBD diagnosis was 1.9±0.3 years, the majority (n = 174, 86.6%) of the participants had UC, 80.1% (n = 161) of the participants had received steroids, and 5.5% of the sample had a history of a surgical stoma. The medical comorbidities among the participants were cerebrovascular accidents (24.9%), hypertension (24.5%), and diabetes mellitus (23.9%). The prevalence of depressive symptoms was 23.4%. The logistic regression analysis resulted in four independent predictors of depression: being female (OR = 2.090,
p = 0.047), history of surgical stoma (OR = 5.737,
p < 0.001), comorbid diagnosis of hypertension (OR = 2.846,
p = 0.007), and history of a cerebrovascular accident (OR = 2.651,
p = 0.011).
CONCLUSIONS: Depressive symptoms are prevalent among Omani patients with IBD. Certain clinical factors appeared to increase the risk of depression among this population. The findings of this study fill a gap in the existing literature and call for further work aiming at screening and managing depression among IBD patients.
AB - OBJECTIVES: Many studies suggest that depression is prevalent among patients suffering from inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Both depression and IBD have a significant disease burden. However, these studies have mostly been conducted among European and American populations and there is a paucity of studies from Arab countries. This study aimed to examine the prevalence and predictors of depressive symptoms among adult IBD patients attending a tertiary care hospital in Muscat, Oman.METHODS: We conducted a cross-sectional study among a random sample of patients aged ≥ 18 years who attended the gastroenterology clinic at Sultan Qaboos University Hospital, Muscat, Oman, between June 2018 and January 2019. Participants were asked to complete the Patient Health Questionnaire-9, which is used to assess depression, and a sociodemographic survey. Logistic regression analysis was used to identify the independent predictors of depressive symptoms among the study sample. Adjusted odds ratios (aORs) were also reported.RESULTS: This study included 201 participants, with an average age of 36 years. Just over half (51.2%) of participants were female. The mean duration of the patients' IBD diagnosis was 1.9±0.3 years, the majority (n = 174, 86.6%) of the participants had UC, 80.1% (n = 161) of the participants had received steroids, and 5.5% of the sample had a history of a surgical stoma. The medical comorbidities among the participants were cerebrovascular accidents (24.9%), hypertension (24.5%), and diabetes mellitus (23.9%). The prevalence of depressive symptoms was 23.4%. The logistic regression analysis resulted in four independent predictors of depression: being female (OR = 2.090,
p = 0.047), history of surgical stoma (OR = 5.737,
p < 0.001), comorbid diagnosis of hypertension (OR = 2.846,
p = 0.007), and history of a cerebrovascular accident (OR = 2.651,
p = 0.011).
CONCLUSIONS: Depressive symptoms are prevalent among Omani patients with IBD. Certain clinical factors appeared to increase the risk of depression among this population. The findings of this study fill a gap in the existing literature and call for further work aiming at screening and managing depression among IBD patients.
KW - Colitis, Ulcerative
KW - Crohn Disease
KW - Cross-Sectional Studies
KW - Depression
KW - Oman
KW - Patient Health Questionnaire
KW - Prevalence
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UR - http://www.scopus.com/inward/citedby.url?scp=85128163225&partnerID=8YFLogxK
U2 - 10.5001/omj.2022.48
DO - 10.5001/omj.2022.48
M3 - Article
C2 - 35356371
AN - SCOPUS:85128163225
SN - 1999-768X
VL - 37
SP - e352
JO - Oman Medical Journal
JF - Oman Medical Journal
IS - 2
M1 - e352
ER -