TY - JOUR
T1 - Bleomycin and perioperative care
T2 - A case report
AU - Jayakrishnan, B.
AU - Kausalya, Rajini
AU - Al-Rashdi, Hilal Ali
AU - Davis, Kirubakaran
AU - Ali, Jahfar
AU - Al-Harthy, Munjid
AU - Bennji, Sami M.
N1 - Publisher Copyright:
© 2023 Mattioli 1885. All rights reserved.
PY - 2023/9/13
Y1 - 2023/9/13
N2 - Bleomycin is associated with pulmonary toxicity ranging from pneumonitis, pulmonary fibrosis, to fatal acute respiratory distress syndrome. Oxygen administration can potentiate or precipitate bleomycin pulmonary toxicity, and the most common setting of oxygen exposure is during anesthesia. We report here the successful management and perioperative care of a patient with documented bleomycin pulmonary toxicity who had to undergo an eight hour long retroperitoneal surgery. With proper preoperative assessment, chest physiotherapy, inhaled steroids and bronchodilators, antibiotics, perioperative restriction of oxygen and fluids and good postoperative care no further pulmonary insult was inflicted.
AB - Bleomycin is associated with pulmonary toxicity ranging from pneumonitis, pulmonary fibrosis, to fatal acute respiratory distress syndrome. Oxygen administration can potentiate or precipitate bleomycin pulmonary toxicity, and the most common setting of oxygen exposure is during anesthesia. We report here the successful management and perioperative care of a patient with documented bleomycin pulmonary toxicity who had to undergo an eight hour long retroperitoneal surgery. With proper preoperative assessment, chest physiotherapy, inhaled steroids and bronchodilators, antibiotics, perioperative restriction of oxygen and fluids and good postoperative care no further pulmonary insult was inflicted.
KW - bleomycin
KW - cancer
KW - oxygen
KW - perioperative care
KW - pulmonary toxicity
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UR - https://www.mendeley.com/catalogue/8c277a01-49f1-30c1-970a-5faccbb55ba8/
U2 - 10.36141/svdld.v40i3.14385
DO - 10.36141/svdld.v40i3.14385
M3 - Article
C2 - 37712370
AN - SCOPUS:85173688163
SN - 1124-0490
VL - 40
SP - e2023030
JO - Sarcoidosis Vasculitis and Diffuse Lung Diseases
JF - Sarcoidosis Vasculitis and Diffuse Lung Diseases
IS - 3
M1 - e2023030
ER -