Abstract
Two novel flavonoid derivatives 5 and 6 were synthesized and characterized by IR, 1H, 13C NMR spectroscopy and mass spectrometry. The core structure of the two flavonoids was constructed by applying Baker-Venkataraman rearrangement on 2-Acylphenyl ester intermediate. The two compounds exhibited remarkable UV-visible absorption activities compared to flavone. Flavonoid 5 showed a bathochromic shift of 75.6 nm when the size of the cinnamic acid was increased by phenylbutadienyl group and hence it is a good UVA sunscreen. The 4-nitrostyryl group introduced in the cinnamic acid subchromophore of flavonoid 6 causes the compound to absorb at 308.3 and at 345.8 nm which will make it a broad-spectrum sunscreen.
Original language | English |
---|---|
Pages (from-to) | 1103-1107 |
Number of pages | 5 |
Journal | Asian Journal of Chemistry |
Volume | 29 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2017 |
Externally published | Yes |
Keywords
- Baker-Venkataraman rearrangement
- Bathochromic shit.
- Flavonoids
- Sunscreens
- UV-visible absorption
ASJC Scopus subject areas
- Chemistry(all)